Bruker ForceRobot 400 BioAFM

Forces play a crucial role in molecular mechanisms, such as recognition, response, and signaling. The ForceRobot® 400 BioAFM incorporates a number of unique force spectroscopy innovations to measure forces at the single-molecule level. It enables the quantification of the mechanical strength of individual molecular bonds and characterisation of the force-dependent properties of molecular interactions and biomolecular complexes.

Features:

• 350,000 force curves per day

• Fully automated single-molecule force spectroscopy (SMFS) capabilities

• Statistically relevant, standardised datasets requried in biomedical and preclinical research

• Advanced force curve designs and extensive fitting routines for flexible experiments

Use ForceRobot 400 to study:

• Protein function at the molecular level

• Molecular biomechanics and receptor-ligand type bonds

• Detection and kinetics of novel antibody-antigen complex formations for immunodiagnostics

• Viscoelastic properties of various materials

• Maximum adhesion force, mechanisms of individual binding and unbinding events

• Intramolecular properties of individual mlecules and molecular arrangements

• Structural changes in macromolecules