Dragonfly 600 from Andor introduces three ground-breaking features; a new total internal reflection fluorescence (TIRF) modality: Borealis TIRF (B-TIRF), a high-power laser engine, and a unique design of 3D Super-Resolution module which retains parfocality across all imaging modes. These technical innovations, combined with innovative software, extend Dragonfly’s capabilities to excel at single molecule localisation microscopy, delivering results with nanometre precision.
This new flagship product also maintains the benefits that position Dragonfly as the leading confocal microscope in the market: it is 10 times faster than point scanner confocals, it images very deep into thick organisms, and it allows users to image live specimens for days without phototoxicity or photobleaching.
An increasingly wide range of questions can now be answered using Dragonfly 600. Cancer and neuroscience research are just two important fields that will benefit from this ground-breaking and hugely flexible system. In spatial transcriptomics experiments, the high laser powers help to reduce acquisition times and contribute to high throughput for emerging applications such as mapping brain transcripts or phenotyping cancer gene expression. Cell biologists will be able to uncover the ultrastructural organisation of organelles or cellular membranes with resolutions an order of magnitude greater than the diffraction limit of light.
Flexibility and ease of use are enabled through open-source Picasso software, adapted for seamless data exchange, and enabling localisations with nanometre precision. Meaningful statistics and beautifully rendered images are then delivered through Oxford Instruments’ market-leading image analysis software, Imaris 10.0.
