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Webinar : Photothermal AFM-IR: Enhanced Analysis Capabilities for Life Science Research

Webinar : Photothermal AFM-IR: Enhanced Analysis Capabilities for Life Science Research

Date: Thursday 26 June 2025
Time: 3am NZST | 1am AEST | 11pm AWST (25 June)
If you are not a night owl, please register for the event and the recording will be sent to you

Nanoscale infrared microscopy enables label-free, chemical imaging, and spectroscopy at the nanometre scale by combining atomic force microscopy (AFM) with infrared radiation. Photothermal AFM-IR allows the simultaneous analysis of the chemical, mechanical, and structural properties of materials and heterogeneous biological matter, such as single-molecules and individual monolayers.

Highlights will include:

  • Overview of the working principle of Photothermal AFM-IR
  • Latest technical advances
  • Outline of modes suitable for biological samples, their advantages and limitations
  • Innovative applications in life science research


Dr. Francesco Simone Ruggeri will speak about the photothermal AFM-IR technique and using it to determine the molecular fingerprint of biomolecules, the secondary structure of protein and their assemblies, and unravel protein phase transitions in healthy and diseased states.

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