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BioAFM Update Webinar : Improved Spatial and Temporal Resolution

Wednesday 1 December 2021, 2pm AEDT


As the value of Atomic Force Microscopy (AFM) in life science has been increasingly recognised, its applications have been expanded well beyond the basic topography and nanomechanical characterisation. Efforts have been devoted to improving the performance of AFM and innovating new functionalities. For example, the limits of spatiotemporal resolution have been abidingly pushed to resolve detailed features or dynamic events at bio samples; sophisticated models and specialised hardware have been introduced to not only improve the accuracy of nanomechanical measurements, but also make dynamic mechanical analysis at nanoscale possible; seamless integration to other optical technologies makes AFM no longer a standalone tool but a multi-functional analysis platform.

In this webinar, we are going to share the recent developments on BioAFM, and more importantly, to showcase how these improvements and innovations have helped solve practical questions researchers have been keen to answer.

Speaker Bio:
Dr. Yun Chen works as Application Scientist at Bruker Nano Surfaces, focusing on exploring application and providing technical support of surface metrology and tribology instruments. He was academically trained in biomedical engineering, biotechnology, and physical chemistry. His PhD work in University of Groningen, Netherlands focused on investigating bacterial behaviors on various biomaterial surfaces. Before joining Bruker, Yun pursued his academic career in Leeds University, UK, working on resolving molecular interactions and kinetics involved in the initial stage of amyloid formation. 

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Benchtop Confocal Microscope

Andor Technology, an Oxford Instruments company and world leader in scientific imaging solutions, today announced the addition of BC43, a revolutionary benchtop confocal system, to its award-winning microscopy portfolio.


An affordable and high-speed confocal microscope, with a small footprint, BC43 is purposefully easy to use, allowing researchers to save time while capturing amazing 3D images. Every component has been designed from the bottom up with performance and accessibility in mind.


Typically, microscopes capturing in 3D are expensive, complex to use and are located in specialised darkroom facilities. This is especially true for confocal technology, which delivers the highest quality 3D images, particularly in thick and more clinically relevant specimens.


Andor will change this with BC43, delivering 2D confocal images in milliseconds and generating 3D views in real-time for immediate scrutiny. The compact design means it can sit on a bench in a regular lab, saving space and time.


BC43 offers a comprehensive imaging experience, handling scales from subcellular detail at single cell level right through to large model organisms and huge tissue samples, and does so in samples thicker than many microscopes are capable of handling.


Ideal for early-stage researchers and experienced microscopists alike, BC43 is simple enough to allow users to capture images within an hour of first using the device, yet sophisticated enough to address complex imaging needs for both live and fixed specimens.


The result is many more researchers empowered to capture outstanding images as part of their regular workflow and many times faster than other confocal microscopes.


For further infromation please contact us, read more or view the product development video.

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New Upright Microscope

Nikon Corporation is pleased to announce the release of the Eclipse Ci-L plus biological microscope.


Long term microscope users know all too well the issues of back and neck strain along with eye fatigue associated with operating and observing specimens under a microscope every day. To reduce these common fatigue problems, Nikon has designed the Eclipse Ci-L plus biological microscope with the intent of eliminating unnecessary operator movements while maintaining the high optical performance of the existing model, the Eclipse Ci-L. The Eclipse Ci-L plus enables users to concentrate on their observations and helps reduce fatigue associated with repetitive microscope operation.



  • LIM (Light Intensity Management) helps reduce eye strain by preventing sudden light intensity changes after changing magnifications
  • Ergonomic design contributes to reducing physical strain
  • Front panel display enables confirmation of magnification and illumination status at a glance
  • Scale bar adjustment linked to nosepiece rotation for more efficient observation
  • Automatic shut-off with ECO mode


For further information please contact us or read more.

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Supercharged Calcium Imaging

CoolLED are excited to introduce their new LED microscope illuminator for lightning-fast calcium imaging, pH monitoring, rtiometric fluorescence, FRET and everyday fluorescence micrsocopy, the pE-800fura


Fluorescence freedom : 8 powerful LED's span 340-635nm to cover all popular calcium and pH indicators, fluorophores and opsins from Fura-2 to Cy5.

Lightning-fast microscopy : Capture dynamic events at the highest temporal resolution and enhance the accuracy of ratiometric measurements with <7µs TTl triggering

Affordable automation: Inline excitation filters and our unique Sequence Runner for triggering illumination sequences with just a single TTL-out of a camera transforms a manual microscope into a powerful automated imaging system.
Low phototoxicity: Comprehensive controls such as fine irradiance modulation and individual channel switching protect samples from phototoxicity and photobleaching, also pushing the boundaries of time-lapse imaging.

Simply better control: In addition to electronic, analogue and GUI control via The LightBridge, full support is available in several imaging software platforms, including NIS Elements and µManager. Integration in cellSens is achieved using the pE-6501-8-FR USB controlled TTL trigger box.


Fur further information please read more, contact us or watch the video tutorials.

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Fast Line-scanning Confocal Microscope

Welcome to the family NL5 !

  • Fast scanning speed: 25fps
  • Perfect for deep 3D confocal imaging
  • Live-cell friendly
  • Easy to use & compact
  • Add-on to existing microscope (inverted and upright), left or right port

For further infromation please contact us, read more or book an online demo.

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