News

Compact and Upgradeable Benchtop Fluorescence Microscope

Date: Wednesday 19 June 2024

Time: 3am NZST, 1am AEST, 11am AWST

If you are not a night owl register for the webinar and you will receive a copy after the event :)
 

With the latest expansion of our Benchtop Microscope range, adding application and budget-based flexibility to the original BC43 Benchtop Confocal. We can now offer more choice and scales of imaging for Neuroscience studies. Our Benchtop Microscopes now start with motorised multi-dimensional widefield fluorescence imaging and extend into super-resolution range.

 

We will introduce our new products and the different imaging modalities of widefield, confocal and super-resolution fluorescence microscopy. The typical biological models and experiments those modalities can be optimally used with will be discussed.

 

Learning Objectives

• Learn about the new extended BC43 product range
• Insight into different imaging modes (widefield, confocal and super-resolution) and how they can be applied to typical neuroscience research models and experiments.
• Understanding the achievable multiple scales of imaging.

 

Geraint Wilde attained a Ph.D. in Neuroscience in 1997 from the University of Southampton, UK, and then continued in the field with a postdoctoral position at the University of Warwick, UK. Having developed an interest in microscopy during his Ph.D. and post doc, he moved to the University of Liverpool, UK, to work in the laboratory of Michael White, focusing on intracellular signalling and gene expression through live-cell imaging. Geraint then left academia to pursue a commercial career in microscopy, starting as a Sales Application Specialist for general life science microscopy where he was exposed to an even broader range of microscope technology and most importantly applications. He joined Andor Technology in 2009, where he is now Hardware Business Manager for Microscopy and Life Science Cameras and the Product Manager for the Andor Benchtop Microscopes.

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Expanding the Dragonfly Series

Oxford Instruments Andor, a world leader in scientific imaging solutions, today announces the launch of Dragonfly 400 and new VLE (Versatile Laser Engine), further expanding the award-winning Dragonfly confocal microscopy portfolio.

 

The Dragonfly 200 series offers speed, sensitivity and excellent confocal imaging, making it an ideal system for a wide range of applications, including live cell imaging, development biology, neurobiology, and cancer research. The Dragonfly 200 delivers high-performance spinning disk confocal imaging of all (thick, thin, fixed and live) biological samples. High-resolution image stacks are ready for analysis in mere seconds.

 

The upgraded model adds new capabilities including the new VLE (Versatile laser engine), which allows seven laser lines in a single chassis and up to 10 lines in dual chassis mode, giving researchers the capability to choose more fluorophores for their experiments as well as increasing labelling options on a single experiment. Furthermore, the Dragonfly series is built with modularity in mind, allowing Dragonfly 200 systems to be upgraded to the new Dragonfly 400 model in the field.

 

The new Dragonfly 400 series builds on the key features of the Dragonfly 200 by adding the established HLE (High Power Laser engine) and the 3D-Super Resolution Module. With the Dragonfly 400 series and the high-power laser engine (HLE), the system becomes ideal for an even wider set of research applications. The HLE delivers enough power for super-resolution applications (SMLM) with DNA-PAINT. A single plane image through the 3D super-resolution module delivers axial information over an ~1 μm range with a corresponding axial resolution down to 30 nm. The high-power lasers of the HLE deliver an increase in productivity over the Dragonfly 200 series, allowing even higher productivity in time-consuming applications, such as spatial omics applications and large sample imaging.

 

For the ultimate range of imaging applications, users have the option of choosing the Dragonfly 600 series with Borealis-TIRF and Zoom Illumination optics imaging functionality to make a complete multi-modal system for widefield, Confocal, TIRF, and SMLM (DNA-PAINT & dSTORM) applications. Dragonfly 600 has achieved impressive resolutions down to 6 nm (DNA-PAINT) and allows SMLM in any imaging modality (confocal, widefield, or B-TIRF).

 

For further information please contact Mark Richardson or read more.

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New Bruker NanoWizard Pure BioAFM

Bruker Nanosurfaces introduce the NanoWizard PURE BioAFM, the latest addition to the Bruker BioAFM product family.

 

Based on the renowned NanoWizard technology platform, its new streamlined design delivers best-in-class performance, combining innovation and functionality in a quality instrument.

 

Discover unrivalled capabilities:

• PeakForce Tapping and QI modes for high-resolution imaging and advanced force control on delicate samples
• Integration with advanced optical microscopy techniques
• Outstanding modularity enables versatility and upgrade options

For further information please contact Michael Buckett or read more.

 

Image credit:

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Oxford Instruments Andor Launches Two New Benchtop Microscopes

Oxford Instruments Andor, a world leader in scientific imaging solutions, today announced the launch of two new benchtop microscopes.

 

Following the successful introduction of the BC43 CF benchtop confocal microscope in 2021, Andor now offers benchtop fluorescence and super resolution models, all have been designed with cost, performance, and accessibility in mind.

 

The BC43 range will bring instant clarity and depth to research studies, whatever the sample, in ways previously only found in larger, more complex, and more expensive systems. The aim of the portfolio expansion is to make fluorescence, confocal, and super resolution microscopy accessible to a much wider user base across different research areas and experience levels.

 

The new BC43 WF is a compact, easy-to-use, and affordable widefield microscope, ideal for automated imaging and smaller budgets. This entry-level system enables hassle-free, high-quality fluorescence imaging, and its in-field upgradability allows researchers to extend into confocal and super-resolution microscopy as requirements or budgets increase.

 

Completing the portfolio is BC43 SR, a microscope that delivers super resolution data quicker and easier than ever before, resolving samples down to 140 nm.

 

Crucially, optical performance is backed up by Andor’s new IQ / OQ quality control programme, which ensures that all BC43 microscopes operate within tightly controlled parameters, and provides confidence that data and experiments are reproducible in the future. This has been developed in collaboration with QUAREP-LiMi, an initiative with over 600 members from academia and industry, which is aiming to improve the reproducibility of light microscopy experiments.

 

More modalities. More performance. More Certainty.

 

For further information please contact us or read more.

 

Image credit : Pancreatic ductal adenocarcinoma cells inside and on top of a 3D hydrogel. DNA is blue, lamin A/C is green, and tubulin is orange. Image credit: Sebastian Amos and Yu Suk Choi, University of Western Australia

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Webinar : Explore the World of BioAFM with Bruker's Experts

Date: Friday 19 April 2024
Time: 5am NZST, 3am AEST, 1am AWST

 

 

If you are not a night owl register for the webinar and you will receive a copy after the event :)

 

Are you looking to dive deeper into the capabilities of your BioAFM? Do you want to learn about the latest advancements in the field? Are you ready to enhance your experimental skills with practical tips and advanced techniques? Then this is the place for you! Whether you’re a seasoned user or new to the field, this is the perfect opportunity to get YOUR questions answered. Join us on April 18, 2024 to engage directly with Bruker’s specialists in a live, user-driven Q&A session and case-based discussion.

 

Webinar Speakers
Yi Wei, Ph.D. Applications Scientist, Bruker
Ming Ye, Ph.D. Applications Scientist, Bruker

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