Bruker ForceRobot 400 BioAFM
Bruker ForceRobot 400 BioAFM
High-throughput, quantitative single-molecule biomechanics
Forces play a crucial role in molecular mechanisms, such as recognition, response, and signaling. The ForceRobot® 400 BioAFM incorporates a number of unique force spectroscopy innovations to measure forces at the single-molecule level. It enables the quantification of the mechanical strength of individual molecular bonds and characterisation of the force-dependent properties of molecular interactions and biomolecular complexes.
Features:
- 350,000 force curves per day
- Fully automated single-molecule force spectroscopy (SMFS) capabilities
- Statistically relevant, standardised datasets requried in biomedical and preclinical research
- Advanced force curve designs and extensive fitting routines for flexible experiments
Use ForceRobot 400 to study:
- Protein function at the molecular level
- Molecular biomechanics and receptor-ligand type bonds
- Detection and kinetics of novel antibody-antigen complex formations for immunodiagnostics
- Viscoelastic properties of various materials
- Maximum adhesion force, mechanisms of individual binding and unbinding events
- Intramolecular properties of individual mlecules and molecular arrangements
- Structural changes in macromolecules
For further information please contact us or download the datasheet.