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Nikon AX/AX R Confocal Microscope System

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Nikon AX/AX R Confocal Microscope System

Nikon AX/AX R Confocal Microscope System

The new standard in confocal imaging


Confocal microscopes have been commercially available now for over 25 years. How can newer iterations of a fundamentally simple instrument continue to innovate? What changes can redefine how a confocal is used, and what data can be collected? Introducing the Nikon AX/AX R Confocal Microscope System, our 10th generation point scanning confocal, giving you more of everything: Leveraging Artificial Intelligence (AI), expanding the number of colors, improving pixel density, sensitivity and speed.

These are significant additions in terms of expanding the range of experiments possible with a point scanning confocal, while increasing the usability and functionality of the instrument, all in a modular and upgradable platform. View images and videos in the Gallery.


See more of the specimen : With the largest field-of-view on both inverted and upright microscope stands available (25mm diagonal), more specimens fit in one FOV with more objective lens choices than ever before. Coupled with scanning sizes up to 8192 x 8192 pixels, sampling beyond the optical diffraction limit is possible even at low magnifications with the AX/AX R.

Right: Whole mouse bladder optically cleared with iDISCO and acquired at 8192 x 8192 pixels using a 2x Plan Apo objective, effective pixel size 0.6 μm (over 5x the spatial resolution of a typical monochrome CMOS camera). Courtesy of Dr. Gerry Apodaca, Integrative Systems Biology, Department of Medicine, University of Pittsburgh in collaboration with Dr. Alan Watson at the Center for Biological Imaging, University of Pittsburgh.


Observe with minimal disturbance : The AX R’s high speed resonant scanning, which decreases the illumination time by more than 20x typical confocal scanning times, greatly reduces biases caused by merely acquiring images. Reducing the acquisition time also allows for extremely high-speed imaging (up to 720 fps @ 2048 x 16). The result: longer imaging and/or more frequent imaging at high speed of living samples which allows capture of dynamic events, but also allows longer time-lapse imaging or significantly faster collection times on fixed specimens.


Acquire more rapidly : Confocal imaging, notoriously slow because of its point-scanning requirement for high quality 3-dimensional imaging at high resolution, is greatly changed by fast imaging with the AX R’s resonant scanning capabilities.


Ultrafine detail : With a full 25mm FOV, up to 8192 x 8192 pixels, and the capability for supravideo frame rates, the AX/AX R allows for spectacular imaging with high resolution, at both low and high magnifications. The entire range of a whole organism or system biology down to intracellular imaging is achievable on one instrument.


For further information please contact us or download the brochure.


AX AXR brochure                                                              Read more on Nikon's website