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Nikon N-SIM S Super Resolution Microscope

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Nikon N-SIM S Super Resolution Microscope

Nikon N-SIM S Super Resolution Microscope

Doubling the conventional resolution limit of live cell time-lapse imaging



  • High-speed super-resolution imaging at 15fps enabling super-resolution time-lapse imaging of live cells and intracellular dynamics
  • Live-cell imaging at double the resolution of conventional light microscopes enabling detailed visualisation of minute intracellular structures and their interactive functions
  • Automatic switching between illumination modes and automated optimisation of structured illumination patterns for different wavelengths and magnificaitons
  • Acquire larger fields of view
  • Various observation modes; TIRF-SIM/2D-SIM, 3D-SIM
  • Simultaneous two-channel imaging
  • Seamless switching between imaging modalities for multi-scale experiments: A desired location in a sample can be specified in a low-magnificaiton/large FOV confocal image and acquired in super-resolution by simply switching the imaging method
  • Objectives for super-resolution microscopes

For further information please contact us or download the datasheet.


      Super-resolution image (3D-SIM)                                                Conventional widefield image

Endoplasmic reticulum (ER) in living HeLa cell labeled with GFP
Objective: CFI Apochromat TIRF 100XC Oil (NA 1.49)
Image capturing speed : approximately 1.3fps (movie)
Reconstruction method: slice
Photographed with the cooperation of: Dr. Ikuo Wada, Institute of Biomedical Sciences, Fukushima Medical University School of Medicine


N-SIM N-STORM brochure                                                          Read more on Nikon's website


Microscope Objectives brochure